Calcitonin is a hormone produced by special cells in the thyroid called C-cells. The thyroid is a small butterfly-shaped gland that lies over and flat against the windpipe in the throat. It produces calcitonin and several hormones that help control the rate of metabolism, primarily thyroxine (T4) and triiodothyronine (T3). This test measures the amount of calcitonin in the blood.